Multiplex T Cell Stimulation Assay Utilizing a T Cell Activation Reporter-Based Detection System

Multiplex T Cell Stimulation Assay Utilizing a T Cell Activation Reporter-Based Detection System

Recent advancements in single cell sequencing technologies allow for identification of numerous immune-receptors expressed by T cells such as tumor-specific and autoimmune T cells. Determining antigen specificity of those cells holds immense therapeutic promise. Therefore, the purpose of this study...

Full description

Bibliographic Details
Main Authors: Sarah E. Mann, Zhicheng Zhou, Laurie G. Landry, Amanda M. Anderson, Aimon K. Alkanani, Jeremy Fischer, Mark Peakman, Roberto Mallone, Kristen Campbell, Aaron W. Michels, Maki Nakayama
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Immunology
Subjects:
antigens
epitopes
T cell receptors
multiplex assay
reporter
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00633/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.00633/full

Similar Items