Stanniocalcin-1 protects retinal ganglion cells by inhibiting apoptosis and oxidative damage.

Optic neuropathy including glaucoma is one of the leading causes of irreversible vision loss, and there are currently no effective therapies. The hallmark of pathophysiology of optic neuropathy is oxidative stress and apoptotic death of retinal ganglion cells (RGCs), a population of neurons in the c...

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Bibliographic Details
Main Authors: Sang Jin Kim, Jung Hwa Ko, Ji-Hyun Yun, Ju-A Kim, Tae Eun Kim, Hyun Ju Lee, Seok Hwan Kim, Ki Ho Park, Joo Youn Oh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3646795?pdf=render