Assessment of computational methods for the analysis of single-cell ATAC-seq data

Assessment of computational methods for the analysis of single-cell ATAC-seq data

Abstract Background Recent innovations in single-cell Assay for Transposase Accessible Chromatin using sequencing (scATAC-seq) enable profiling of the epigenetic landscape of thousands of individual cells. scATAC-seq data analysis presents unique methodological challenges. scATAC-seq experiments sam...

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Bibliographic Details
Main Authors: Huidong Chen, Caleb Lareau, Tommaso Andreani, Michael E. Vinyard, Sara P. Garcia, Kendell Clement, Miguel A. Andrade-Navarro, Jason D. Buenrostro, Luca Pinello
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Genome Biology
Subjects:
scATAC-seq
Feature matrix
Benchmarking
Regulatory genomics
Clustering
Visualization
Online Access:http://link.springer.com/article/10.1186/s13059-019-1854-5

Internet

http://link.springer.com/article/10.1186/s13059-019-1854-5

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