Identification of distinct tumor cell populations and key genetic mechanisms through single cell sequencing in hepatoblastoma

Bondoc et al perform single-cell RNA-Seq profiling of Hepatoblastoma, background liver, and patient-derived xenografts to investigate cell-type heterogeneity and characterise the driver malignant cell cluster.

Bibliographic Details
Main Authors: Alexander Bondoc, Kathryn Glaser, Kang Jin, Charissa Lake, Stefano Cairo, James Geller, Gregory Tiao, Bruce Aronow
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02562-8