Identification of distinct tumor cell populations and key genetic mechanisms through single cell sequencing in hepatoblastoma
Bondoc et al perform single-cell RNA-Seq profiling of Hepatoblastoma, background liver, and patient-derived xenografts to investigate cell-type heterogeneity and characterise the driver malignant cell cluster.
Main Authors: | Alexander Bondoc, Kathryn Glaser, Kang Jin, Charissa Lake, Stefano Cairo, James Geller, Gregory Tiao, Bruce Aronow |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-09-01
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Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-021-02562-8 |
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