Norrin Protects Retinal Ganglion Cells from Excitotoxic Damage via the Induction of Leukemia Inhibitory Factor

Norrin Protects Retinal Ganglion Cells from Excitotoxic Damage via the Induction of Leukemia Inhibitory Factor

Purpose: To investigate whether and how leukemia inhibitory factor (Lif) is involved in mediating the neuroprotective effects of Norrin on retinal ganglion cells (RGC) following excitotoxic damage. Norrin is a secreted protein that protects RGC from <i>N-</i>methyl-<span style="f...

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Bibliographic Details
Main Authors: Stefan Kassumeh, Stephanie Leopold, Rudolf Fuchshofer, Carina N. Thomas, Siegfried G. Priglinger, Ernst R. Tamm, Andreas Ohlmann
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Cells
Subjects:
lif
retinal ganglion cells
neuroprotection
excitotoxic damage
nmda
apoptosis
norrin
wnt/β-catenin signaling
Online Access:https://www.mdpi.com/2073-4409/9/2/277

Internet

https://www.mdpi.com/2073-4409/9/2/277

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