GOLPH3 Regulates EGFR in T98G Glioblastoma Cells by Modulating Its Glycosylation and Ubiquitylation

GOLPH3 Regulates EGFR in T98G Glioblastoma Cells by Modulating Its Glycosylation and Ubiquitylation

Protein trafficking is altered when normal cells acquire a tumor phenotype. A key subcellular compartment in regulating protein trafficking is the Golgi apparatus, but its role in carcinogenesis is still not well defined. Golgi phosphoprotein 3 (GOLPH3), a peripheral membrane protein mostly localize...

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Bibliographic Details
Main Authors: Cecilia Arriagada, Viviana A. Cavieres, Charlotte Luchsinger, Alexis E. González, Vanessa C. Muñoz, Jorge Cancino, Patricia V. Burgos, Gonzalo A. Mardones
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:International Journal of Molecular Sciences
Subjects:
EGFR
glioblastoma multiforme
glycosylation
Golgi apparatus
GOLPH3
protein trafficking
Online Access:https://www.mdpi.com/1422-0067/21/22/8880

Internet

https://www.mdpi.com/1422-0067/21/22/8880

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