Structure-activity relationships of the antimicrobial peptide arasin 1 - and mode of action studies of the N-terminal, proline-rich region.

Structure-activity relationships of the antimicrobial peptide arasin 1 - and mode of action studies of the N-terminal, proline-rich region.

Arasin 1 is a 37 amino acid long proline-rich antimicrobial peptide isolated from the spider crab, Hyas araneus. In this work the active region of arasin 1 was identified through structure-activity studies using different peptide fragments derived from the arasin 1 sequence. The pharmacophore was fo...

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Bibliographic Details
Main Authors: Victoria S Paulsen, Hans-Matti Blencke, Monica Benincasa, Tor Haug, Jacobus J Eksteen, Olaf B Styrvold, Marco Scocchi, Klara Stensvåg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3543460?pdf=render

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http://europepmc.org/articles/PMC3543460?pdf=render

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