SENP2 is vital for optimal insulin signaling and insulin-stimulated glycogen synthesis in human skeletal muscle cells

SENP2 is vital for optimal insulin signaling and insulin-stimulated glycogen synthesis in human skeletal muscle cells

Sentrin-specific protease (SENP) 2 has been suggested as a possible novel drug target for the treatment of obesity and type 2 diabetes mellitus after observations of a palmitate-induced increase in SENP2 that lead to increased fatty acid oxidation and improved insulin sensitivity in skeletal muscle...

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Bibliographic Details
Main Authors: Jenny Lund, Solveig A. Krapf, Medina Sistek, Hege G. Bakke, Stefano Bartesaghi, Xiao-Rong Peng, Arild C. Rustan, G. Hege Thoresen, Eili T. Kase
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Current Research in Pharmacology and Drug Discovery
Subjects:
SENP2
Lentivirus
Knockdown
Primary human myotubes
Energy metabolism
Insulin sensitivity
Online Access:http://www.sciencedirect.com/science/article/pii/S2590257121000481

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http://www.sciencedirect.com/science/article/pii/S2590257121000481

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