Analyses of regional radiosensitivity of white matter structures along tract axes using novel white matter segmentation and diffusion imaging biomarkers

Background and purpose: Brain radiotherapy (RT) can cause white matter damage and downstream neurocognitive decline. We developed a computational neuroimaging tool to regionally partition individual white matter tracts, then analyze regional changes in diffusion metrics of white matter damage follow...

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Bibliographic Details
Main Authors: Jordan Houri, Roshan Karunamuni, Michael Connor, Niclas Pettersson, Carrie McDonald, Nikdokht Farid, Nathan White, Anders Dale, Jona A. Hattangadi-Gluth, Vitali Moiseenko
Format: Article
Language:English
Published: Elsevier 2018-04-01
Series:Physics and Imaging in Radiation Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S240563161730091X