Effect of integrin α5β1 inhibition on SDF-l/CXCR4- mediated choroidal neovascularization

AIM: To investigate the roles of integrins in choroidal neovascularization (CNV) and their associations with the stromal cell-derived factor-1 (SDF-1)/CXCR4 axis. METHODS: CNV lesions were induced in mice using laser photocoagulation. After CNV induction, all animals were randomly assigned to: cont...

Full description

Bibliographic Details
Main Authors: Yang Lyu, Wen-Qin Xu, Li-Juan Sun, Xiao-Yan Pan, Jian Zhang, Yu-Sheng Wang
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2018-05-01
Series:International Journal of Ophthalmology
Subjects:
735
Online Access:http://www.ijo.cn/en_publish/2018/5/20180504.pdf