Integrative Genomics Analysis Unravels Tissue-Specific Pathways, Networks, and Key Regulators of Blood Pressure Regulation

Integrative Genomics Analysis Unravels Tissue-Specific Pathways, Networks, and Key Regulators of Blood Pressure Regulation

Blood pressure (BP) is a highly heritable trait and a major cardiovascular disease risk factor. Genome wide association studies (GWAS) have implicated a number of susceptibility loci for systolic (SBP) and diastolic (DBP) blood pressure. However, a large portion of the heritability cannot be explain...

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Bibliographic Details
Main Authors: Yuqi Zhao, Montgomery Blencowe, Xingyi Shi, Le Shu, Candace Levian, In Sook Ahn, Stuart K. Kim, Tianxiao Huan, Daniel Levy, Xia Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
blood pressure
genome wide association studies
integrative genomics
regulatory networks
key drivers
Online Access:https://www.frontiersin.org/article/10.3389/fcvm.2019.00021/full

Internet

https://www.frontiersin.org/article/10.3389/fcvm.2019.00021/full

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