Rapid, redox-mediated mechanical susceptibility of the cortical microtubule lattice in skeletal muscle

The highly ordered cortical microtubule lattice of skeletal muscle is disorganized in dystrophin-deficient mdx mice. Implicated mechanisms include loss of dystrophin binding, altered α-tubulin posttranslational modification, expression of a β-tubulin involved in regeneration, and reactive oxygen spe...

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Bibliographic Details
Main Authors: D'anna M. Nelson, Elizabeth K. Fasbender, Margurite C. Jakubiak, Angus Lindsay, Dawn A. Lowe, James M. Ervasti
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:Redox Biology
Subjects:
mdx
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231720309356