Metronidazole- and Amoxicillin-Loaded PLGA and PCL Nanofibers as Potential Drug Delivery Systems for the Treatment of Periodontitis: In Vitro and In Vivo Evaluations

Metronidazole- and Amoxicillin-Loaded PLGA and PCL Nanofibers as Potential Drug Delivery Systems for the Treatment of Periodontitis: In Vitro and In Vivo Evaluations

The purpose of this study was to prepare poly (D-L) lactide-co-glycolide (PLGA) and poly ε-caprolactone (PCL) nanofibers containing metronidazole and amoxicillin using an electrospinning process as intrapocket sustained-release drug delivery systems for the treatment of periodontal diseases. Scannin...

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Bibliographic Details
Main Authors: Shahla Mirzaeei, Mahla Mansurian, Kofi Asare-Addo, Ali Nokhodchi
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Biomedicines
Subjects:
periodontitis
metronidazole
amoxicillin
nanofiber
intrapocket
drug release
Online Access:https://www.mdpi.com/2227-9059/9/8/975

Internet

https://www.mdpi.com/2227-9059/9/8/975

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