ReQON: a Bioconductor package for recalibrating quality scores from next-generation sequencing data

ReQON: a Bioconductor package for recalibrating quality scores from next-generation sequencing data

<p>Abstract</p> <p>Background</p> <p>Next-generation sequencing technologies have become important tools for genome-wide studies. However, the quality scores that are assigned to each base have been shown to be inaccurate. If the quality scores are used in downstream an...

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Bibliographic Details
Main Authors: Cabanski Christopher R, Cavin Keary, Bizon Chris, Wilkerson Matthew D, Parker Joel S, Wilhelmsen Kirk C, Perou Charles M, Marron JS, Hayes D
Format: Article
Language:English
Published: BMC 2012-09-01
Series:BMC Bioinformatics
Subjects:
Next-generation sequencing
Quality score
Recalibration
Bioinformatics
Bioconductor
Online Access:http://www.biomedcentral.com/1471-2105/13/221

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http://www.biomedcentral.com/1471-2105/13/221

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