Epigenetic regulation of IFITM1 expression in lipopolysaccharide-stimulated human mesenchymal stromal cells

Epigenetic regulation of IFITM1 expression in lipopolysaccharide-stimulated human mesenchymal stromal cells

Abstract Background Toll-like receptor 4 (TLR4) ligands such as lipopolysaccharide (LPS) activate immunomodulatory functions and the migration of human mesenchymal stromal cells (hMSCs). Here, we study the migration-related gene expression of LPS-stimulated hMSCs and the role and regulation of one o...

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Bibliographic Details
Main Authors: Sun Hwa Kim, Hae In Choi, Mi Ran Choi, Ga Yeong An, Bert Binas, Kyoung Hwa Jung, Young Gyu Chai
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Stem Cell Research & Therapy
Subjects:
Mesenchymal stromal cells
Interferon-induced transmembrane protein 1
Toll-like receptor 4
Lipopolysaccharide
Enhancer
NF-κB
Online Access:https://doi.org/10.1186/s13287-019-1531-3

Internet

https://doi.org/10.1186/s13287-019-1531-3

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