Osthole Suppresses the Migratory Ability of Human Glioblastoma Multiforme Cells via Inhibition of Focal Adhesion Kinase-Mediated Matrix Metalloproteinase-13 Expression

Osthole Suppresses the Migratory Ability of Human Glioblastoma Multiforme Cells via Inhibition of Focal Adhesion Kinase-Mediated Matrix Metalloproteinase-13 Expression

Glioblastoma multiforme (GBM) is the most common type of primary and malignant tumor occurring in the adult central nervous system. GBM often invades surrounding regions of the brain during its early stages, making successful treatment difficult. Osthole, an active constituent isolated from the drie...

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Bibliographic Details
Main Authors: Cheng-Fang Tsai, Wei-Lan Yeh, Jia-Hong Chen, Chingju Lin, Shiang-Suo Huang, Dah-Yuu Lu
Format: Article
Language:English
Published: MDPI AG 2014-03-01
Series:International Journal of Molecular Sciences
Subjects:
osthole
GBM
FAK
MMP-13
cell migration
Online Access:http://www.mdpi.com/1422-0067/15/3/3889

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http://www.mdpi.com/1422-0067/15/3/3889

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