Loss with ageing but preservation of frontal cortical capillary pericytes in post-stroke dementia, vascular dementia and Alzheimer’s disease

Loss with ageing but preservation of frontal cortical capillary pericytes in post-stroke dementia, vascular dementia and Alzheimer’s disease

Abstract Cerebral pericytes are an integral component of the neurovascular unit, which governs the blood–brain barrier. There is paucity of knowledge on cortical pericytes across different dementias. We quantified cortical pericytes in capillaries in 124 post-mortem brains from subjects with post-st...

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Bibliographic Details
Main Authors: Ren Ding, Yoshiki Hase, Matthew Burke, Vincent Foster, William Stevenson, Tuomo Polvikoski, Raj N. Kalaria
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Acta Neuropathologica Communications
Subjects:
Alzheimer's disease
Cerebral cortex
Collagen IV
Dementia
Pericyte
Platelet derived growth factor receptor
Online Access:https://doi.org/10.1186/s40478-021-01230-6

Internet

https://doi.org/10.1186/s40478-021-01230-6

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