The limitations of the Cepheid GeneXpert® Mtb/Rif assay for the diagnosis and management of polyresistant pulmonary tuberculosis

Background: Tuberculosis (TB) is the leading world-wide cause of death caused by a single infectious agent. The global treatment success rate for multi-drug resistant (MDR) TB, defined as resistance to at least rifampicin and isoniazid, is estimated at 56%. Mutations in the rpoB gene predict resista...

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Bibliographic Details
Main Authors: Dahlia Hopmeier, Temi Lampejo, Julian Rycroft, Simon Tiberi, Mark Melzer
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:Clinical Infection in Practice
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S259017022030025X