The limitations of the Cepheid GeneXpert® Mtb/Rif assay for the diagnosis and management of polyresistant pulmonary tuberculosis
Background: Tuberculosis (TB) is the leading world-wide cause of death caused by a single infectious agent. The global treatment success rate for multi-drug resistant (MDR) TB, defined as resistance to at least rifampicin and isoniazid, is estimated at 56%. Mutations in the rpoB gene predict resista...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-10-01
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Series: | Clinical Infection in Practice |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S259017022030025X |