Degradation of amyloid beta by human induced pluripotent stem cell-derived macrophages expressing Neprilysin-2
The purpose of this study was to evaluate the therapeutic potential of human induced pluripotent stem (iPS) cell-derived macrophage-like cells for Alzheimer's disease (AD). In previous studies, we established the technology to generate macrophage-like myeloid lineage cells with proliferating c...
Main Authors: | Koutaro Takamatsu, Tokunori Ikeda, Miwa Haruta, Keiko Matsumura, Yasuhiro Ogi, Naomi Nakagata, Makoto Uchino, Yukio Ando, Yasuharu Nishimura, Satoru Senju |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2014-11-01
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Series: | Stem Cell Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1873506114001111 |
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