Vaccine adjuvant activity of a TLR4-activating synthetic glycolipid by promoting autophagy

Vaccine adjuvant activity of a TLR4-activating synthetic glycolipid by promoting autophagy

Abstract Toll-like receptors (TLRs) play crucial roles in host immune defenses. Recently, TLR-mediated autophagy is reported to promote immune responses via increasing antigen processing and presentation in antigen presenting cells. The present study examined whether the synthetic TLR4 activator (CC...

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Bibliographic Details
Main Authors: Yi-Ju Chou, Ching-Cheng Lin, Ivan Dzhagalov, Nien-Jung Chen, Chao-Hsiung Lin, Chun-Cheng Lin, Szu-Ting Chen, Kuo-Hsin Chen, Shu-Ling Fu
Format: Article
Language:English
Published: Nature Publishing Group 2020-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-65422-1

Internet

https://doi.org/10.1038/s41598-020-65422-1

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