Novel naphthalene-enoates: Design and anticancer activity through regulation cell autophagy
Eleven dihydroxy-2-(1-hydroxy-4-methylpent-3-enyl)naphthalene derivatives as anticancer agents through regulating cell autophagy were designed and synthesized. The anticancer activity results indicated that most compounds manifested obvious un-toxic effect on GES-1 and L-02 with IC50 from 0.58 to 1....
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-05-01
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Series: | Biomedicine & Pharmacotherapy |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0753332219306869 |