Spontaneous Switching among Conformational Ensembles in Intrinsically Disordered Proteins

The common conception of intrinsically disordered proteins (IDPs) is that they stochastically sample all possible configurations driven by thermal fluctuations. This is certainly true for many IDPs, which behave as swollen random coils that can be described using polymer models developed for homopol...

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Bibliographic Details
Main Authors: Ucheor B. Choi, Hugo Sanabria, Tatyana Smirnova, Mark E. Bowen, Keith R. Weninger
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Biomolecules
Subjects:
IDP
Online Access:https://www.mdpi.com/2218-273X/9/3/114