A Modified Generalized Fisher Method for Combining Probabilities from Dependent Tests

Rapid developments in molecular technology have yielded a large amount of high throughput genetic data to understand the mechanism for complex traits. The increase of genetic variants requires hundreds and thousands of statistical tests to be performed simultaneously in analysis, which poses a chall...

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Bibliographic Details
Main Authors: Hongying (Daisy) eDai, J Steven Leeder, Yuehua eCui
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-02-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00032/full