Developing high-efficiency base editors by combining optimized synergistic core components with new types of nuclear localization signal peptide

Developing high-efficiency base editors by combining optimized synergistic core components with new types of nuclear localization signal peptide

The clustered regularly interspaced short palindromic repeats (CRISPR)–CRISPR-associated protein (Cas) system has been widely used for genome editing. In this system, the cytosine base editor (CBE) and adenine base editor (ABE) allow generating precise and irreversible base mutations in a programmab...

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Bibliographic Details
Main Authors: Feipeng Wang, Chengwei Zhang, Wen Xu, Shuang Yuan, Jinling Song, Lu Li, Jiuran Zhao, Jinxiao Yang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2020-06-01
Series:Crop Journal
Subjects:
Multiplex base editing
NLS
Cytosine base editor
Adenine base editor
Rice
Online Access:http://www.sciencedirect.com/science/article/pii/S2214514120300192

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http://www.sciencedirect.com/science/article/pii/S2214514120300192

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