PLGA/PLA-Based Long-Acting Injectable Depot Microspheres in Clinical Use: Production and Characterization Overview for Protein/Peptide Delivery

PLGA/PLA-Based Long-Acting Injectable Depot Microspheres in Clinical Use: Production and Characterization Overview for Protein/Peptide Delivery

Over the past few decades, long acting injectable (LAI) depots of polylactide-co-glycolide (PLGA) or polylactic acid (PLA) based microspheres have been developed for controlled drug delivery to reduce dosing frequency and to improve the therapeutic effects. Biopharmaceuticals such as proteins and pe...

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Bibliographic Details
Main Authors: Arun Butreddy, Rajendra Prasad Gaddam, Nagavendra Kommineni, Narendar Dudhipala, Chandrashekhar Voshavar
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
PLGA
PLA
proteins/peptides
microspheres
manufacturing techniques
characterization techniques
Online Access:https://www.mdpi.com/1422-0067/22/16/8884

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https://www.mdpi.com/1422-0067/22/16/8884

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