In vivo calcium imaging reveals disordered interictal network dynamics in epileptic stxbp1b zebrafish

Summary: STXBP1 mutations are associated with encephalopathy, developmental delay, intellectual disability, and epilepsy. While neural networks are known to operate at a critical state in the healthy brain, network behavior during pathological epileptic states remains unclear. Examining activity dur...

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Bibliographic Details
Main Authors: Jing Liu, Kathryn A. Salvati, Scott C. Baraban
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221005265