Substrate Elasticity Exerts Functional Effects on Primary Microglia

Substrate Elasticity Exerts Functional Effects on Primary Microglia

Microglia—the brain’s primary immune cells—exert a tightly regulated cascade of pro- and anti-inflammatory effects upon brain pathology, either promoting regeneration or neurodegeneration. Therefore, harnessing microglia emerges as a potential therapeutic concept in neurological research. Recent stu...

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Bibliographic Details
Main Authors: Stefan J. Blaschke, Seda Demir, Anna König, Jella-Andrea Abraham, Sabine U. Vay, Monika Rabenstein, Daniel N. Olschewski, Christina Hoffmann, Marco Hoffmann, Nils Hersch, Rudolf Merkel, Bernd Hoffmann, Michael Schroeter, Gereon R. Fink, Maria A. Rueger
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Cellular Neuroscience
Subjects:
neuroinflammation
microglia
elasticity
polarization
vimentin
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2020.590500/full

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https://www.frontiersin.org/articles/10.3389/fncel.2020.590500/full

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