Gametogenesis in malaria parasites is mediated by the cGMP-dependent protein kinase.

Malaria parasite transmission requires differentiation of male and female gametocytes into gametes within a mosquito following a blood meal. A mosquito-derived molecule, xanthurenic acid (XA), can trigger gametogenesis, but the signalling events controlling this process in the human malaria parasite...

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Bibliographic Details
Main Authors: Louisa McRobert, Cathy J Taylor, Wensheng Deng, Quinton L Fivelman, Ross M Cummings, Spencer D Polley, Oliver Billker, David A Baker
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-06-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC2408617?pdf=render