Generation of hiPSC-Derived Functional Dopaminergic Neurons in Alginate-Based 3D Culture

Generation of hiPSC-Derived Functional Dopaminergic Neurons in Alginate-Based 3D Culture

Human induced pluripotent stem cells (hiPSCs) represent an unlimited cell source for the generation of patient-specific dopaminergic (DA) neurons, overcoming the hurdle of restricted accessibility to disease-affected tissue for mechanistic studies on Parkinson’s disease (PD). However, the complexity...

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Bibliographic Details
Main Authors: Valentina Gilmozzi, Giovanna Gentile, Diana A. Riekschnitz, Michael Von Troyer, Alexandros A. Lavdas, Emanuela Kerschbamer, Christian X. Weichenberger, Marcelo D. Rosato-Siri, Simona Casarosa, Luciano Conti, Peter P. Pramstaller, Andrew A. Hicks, Irene Pichler, Alessandra Zanon
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
three-dimensional culture
hiPSCs
Parkinson’s disease
microencapsulation
alginate
biomaterials
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.708389/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.708389/full

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