Globular Adiponectin Inhibits Breast Cancer Cell Growth through Modulation of Inflammasome Activation: Critical Role of Sestrin2 and AMPK Signaling

Adiponectin, an adipokine predominantly derived from adipose tissue, exhibits potent antitumor properties in breast cancer cells. However, its mechanisms of action remain elusive. Inflammasomes—intracellular multimeric protein complexes—modulate cancer cell growth in a complicate...

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Bibliographic Details
Main Authors: Duc-Vinh Pham, Pawan Kumar Raut, Mahesh Pandit, Jae-Hoon Chang, Nikita Katila, Dong-Young Choi, Jee-Heon Jeong, Pil-Hoon Park
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/12/3/613