EGR2, IGF1 and IL6 Expression Are Elevated in the Intervertebral Disc of Patients Suffering from Diffuse Idiopathic Skeletal Hyperostosis (DISH) Compared to Degenerative or Trauma Discs

EGR2, IGF1 and IL6 Expression Are Elevated in the Intervertebral Disc of Patients Suffering from Diffuse Idiopathic Skeletal Hyperostosis (DISH) Compared to Degenerative or Trauma Discs

Diffuse idiopathic skeletal hyperostosis (DISH) is characterised by ectopic ossification along the anterior spine and the outer intervertebral discs (IVD). However, the centre of the IVD, i.e., the nucleus pulposus, always remains unaffected, which could be due to the inhibition of the bone morphoge...

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Bibliographic Details
Main Authors: Benjamin Gantenbein, Rahel D. May, Paola Bermudez-Lekerika, Katharina A. C. Oswald, Lorin M. Benneker, Christoph E. Albers
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Applied Sciences
Subjects:
low back pain
diffuse idiopathic skeletal hyperostosis
RNA extraction
qPCR
TGFβ-pathway
immune-histochemistry
Online Access:https://www.mdpi.com/2076-3417/11/9/4072

Internet

https://www.mdpi.com/2076-3417/11/9/4072

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