A Multi-Marker Genetic Association Test Based on the Rasch Model Applied to Alzheimer's Disease.

A Multi-Marker Genetic Association Test Based on the Rasch Model Applied to Alzheimer's Disease.

Results from Genome-Wide Association Studies (GWAS) have shown that the genetic basis of complex traits often include many genetic variants with small to moderate effects whose identification remains a challenging problem. In this context multi-marker analysis at the gene and pathway level can compl...

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Bibliographic Details
Main Authors: Wenjia Wang, Jonas Mandel, Jan Bouaziz, Daniel Commenges, Serguei Nabirotchkine, Ilya Chumakov, Daniel Cohen, Mickaël Guedj, Alzheimer’s Disease Neuroimaging Initiative
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4574966?pdf=render

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http://europepmc.org/articles/PMC4574966?pdf=render

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