Emetine Di-HCl Attenuates Type 1 Diabetes Mellitus in Mice

Emetine Di-HCl Attenuates Type 1 Diabetes Mellitus in Mice

Abstract Type 1 diabetes mellitus (T1D) is a chronic autoimmune disease characterized by β cell destruction, insulin deficiency and hyperglycemia. Activated macrophages and autoimmune T cells play a crucial role in the pathogenesis of hyperglycemia in NOD murine diabetes models, but the molecular me...

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Bibliographic Details
Main Authors: LaQueta K Hudson, Meghan E Dancho, Jianhua Li, Johanna B Bruchfeld, Ahmed A Ragab, Mingzhu M He, Meaghan Bragg, Delaney Lenaghan, Michael D Quinn, Jason R Fritz, Matthew V Tanzi, Harold A Silverman, William M Hanes, Yaakov A Levine, Valentin A Pavlov, Peder S Olofsson, Jesse Roth, Yousef Al-Abed, Ulf Andersson, Kevin J Tracey, Sangeeta S Chavan
Format: Article
Language:English
Published: BMC 2016-06-01
Series:Molecular Medicine
Online Access:http://link.springer.com/article/10.2119/molmed.2016.00082

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http://link.springer.com/article/10.2119/molmed.2016.00082

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