From BACE1 Inhibitor to Multifunctionality of Tryptoline and Tryptamine Triazole Derivatives for Alzheimer’s Disease

Efforts to discover new drugs for Alzheimer’s disease emphasizing multiple targets was conducted seeking to inhibit amyloid oligomer formation and to prevent radical formation. The tryptoline and tryptamine cores of BACE1 inhibitors previously identified by virtual screening were modified <em...

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Bibliographic Details
Main Authors: Jutamas Jiaranaikulwanitch, Piyarat Govitrapong, Valery V. Fokin, Opa Vajragupta
Format: Article
Language:English
Published: MDPI AG 2012-07-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/17/7/8312