Active integrins regulate white adipose tissue insulin sensitivity and brown fat thermogenesis

Active integrins regulate white adipose tissue insulin sensitivity and brown fat thermogenesis

Objective: Reorganization of the extracellular matrix is a prerequisite for healthy adipose tissue expansion, whereas fibrosis is a key feature of adipose dysfunction and inflammation. However, very little is known about the direct effects of impaired cell–matrix interaction in adipocyte function an...

Full description

Bibliographic Details
Main Authors: Francisco Javier Ruiz-Ojeda, Jiefu Wang, Theresa Bäcker, Martin Krueger, Samira Zamani, Simon Rosowski, Tim Gruber, Yasuhiro Onogi, Annette Feuchtinger, Tim J. Schulz, Reinhard Fässler, Timo D. Müller, Cristina García-Cáceres, Matthias Meier, Matthias Blüher, Siegfried Ussar
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Molecular Metabolism
Subjects:
Integrins
Kindlin-2
Insulin resistance
Adipose tissue
Obesity
Brown fat
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877820302210

Internet

http://www.sciencedirect.com/science/article/pii/S2212877820302210

Similar Items