Melatonin Induces Melanogenesis in Human SK-MEL-1 Melanoma Cells Involving Glycogen Synthase Kinase-3 and Reactive Oxygen Species

Melatonin Induces Melanogenesis in Human SK-MEL-1 Melanoma Cells Involving Glycogen Synthase Kinase-3 and Reactive Oxygen Species

Melatonin is present in all living organisms where it displays a diversity of physiological functions. Attenuation of melanogenesis by melatonin has been reported in some mammals and also in rodent melanoma cells. However, melatonin may also stimulate melanogenesis in human melanoma cells through me...

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Bibliographic Details
Main Authors: Juan Perdomo, Carlos Quintana, Ignacio González, Inmaculada Hernández, Sara Rubio, Juan F. Loro, Russel J. Reiter, Francisco Estévez, José Quintana
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:International Journal of Molecular Sciences
Subjects:
melatonin
melanogenesis
melanoma
SK-MEL-1
GSK-3β
tyrosinase
Online Access:https://www.mdpi.com/1422-0067/21/14/4970

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https://www.mdpi.com/1422-0067/21/14/4970

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