Neural synchronization deficits linked to cortical hyper-excitability and auditory hypersensitivity in fragile X syndrome

Neural synchronization deficits linked to cortical hyper-excitability and auditory hypersensitivity in fragile X syndrome

Abstract Background Studies in the fmr1 KO mouse demonstrate hyper-excitability and increased high-frequency neuronal activity in sensory cortex. These abnormalities may contribute to prominent and distressing sensory hypersensitivities in patients with fragile X syndrome (FXS). The current study in...

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Bibliographic Details
Main Authors: Lauren E. Ethridge, Stormi P. White, Matthew W. Mosconi, Jun Wang, Ernest V. Pedapati, Craig A. Erickson, Matthew J. Byerly, John A. Sweeney
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Molecular Autism
Subjects:
Fragile X syndrome
EEG
Chirp
Gamma
Sensory
Online Access:http://link.springer.com/article/10.1186/s13229-017-0140-1

Internet

http://link.springer.com/article/10.1186/s13229-017-0140-1

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