Intratracheal transplantation of trophoblast stem cells attenuates acute lung injury in mice

Intratracheal transplantation of trophoblast stem cells attenuates acute lung injury in mice

Abstract Background Acute lung injury (ALI) is a common lung disorder that affects millions of people every year. The infiltration of inflammatory cells into the lungs and death of the alveolar epithelial cells are key factors to trigger a pathological cascade. Trophoblast stem cells (TSCs) are immu...

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Bibliographic Details
Main Authors: Junwen Han, Gu Li, Minmin Hou, Julie Ng, Min-Young Kwon, Kevin Xiong, Xiaoliang Liang, Elizabeth Taglauer, Yuanyuan Shi, S. Alex Mitsialis, Stella Kourembanas, Souheil El-Chemaly, James A. Lederer, Ivan O. Rosas, Mark A. Perrella, Xiaoli Liu
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Stem Cell Research & Therapy
Subjects:
Trophoblast stem cells
Acute lung injury
Inflammation
Alveolar epithelial cells
Engraftment
Online Access:https://doi.org/10.1186/s13287-021-02550-z

Internet

https://doi.org/10.1186/s13287-021-02550-z

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