Evidence for positive selection on a number of MicroRNA regulatory interactions during recent human evolution.
MicroRNA (miRNA)-mediated gene regulation is of critical functional importance in animals and is thought to be largely constrained during evolution. However, little is known regarding evolutionary changes of the miRNA network and their role in human evolution. Here we show that a number of miRNA bin...
Main Authors: | Jingjing Li, Yu Liu, Xiaofeng Xin, Taehyung Simon Kim, Eduardo Aguiar Cabeza, Jie Ren, Rasmus Nielsen, Jeffrey L Wrana, Zhaolei Zhang |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
|
Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC3310733?pdf=render |
Similar Items
-
A Survey of Regulatory Interactions Among RNA Binding Proteins and MicroRNAs in Cancer
by: Ying Liu, et al.
Published: (2020-09-01) -
MicroRNAs and Their Regulatory Role in Sugarcane
by: M. Swapna, et al.
Published: (2017-06-01) -
The Role of MicroRNAs in Regulatory T Cells
by: Chao Liu, et al.
Published: (2020-01-01) -
Regulatory Roles of MicroRNAs in Diabetes
by: Juan Feng, et al.
Published: (2016-10-01) -
MicroRNAs as regulatory elements in psoriasis
by: Liu Yuan, et al.
Published: (2016-01-01)