Clinical and Laboratory Features of JAK2 V617F, CALR, and MPL Mutations in Malaysian Patients with Classical Myeloproliferative Neoplasm (MPN)

Clinical and Laboratory Features of JAK2 V617F, CALR, and MPL Mutations in Malaysian Patients with Classical Myeloproliferative Neoplasm (MPN)

Mutations of JAK2V617F, CALR, and MPL genes confirm the diagnosis of myeloproliferative neoplasm (MPN). This study aims to determine the genetic profile of JAK2V617F, CALR exon 9 Type 1 (52 bp deletion) and Type 2 (5 bp insertion), and MPL W515 L/K genes among Malaysian patients and correlate these...

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Bibliographic Details
Main Authors: Razan Hayati Zulkeflee, Zefarina Zulkafli, Muhammad Farid Johan, Azlan Husin, Md Asiful Islam, Rosline Hassan
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:International Journal of Environmental Research and Public Health
Subjects:
hematologic malignancies
chronic myeloproliferative neoplasm
molecular biology
polycythemia vera
essential thrombocythemia
primary myelofibrosis
Online Access:https://www.mdpi.com/1660-4601/18/14/7582

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https://www.mdpi.com/1660-4601/18/14/7582

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