ERK Pathway in Activated, Myofibroblast-Like, Hepatic Stellate Cells: A Critical Signaling Crossroad Sustaining Liver Fibrosis

ERK Pathway in Activated, Myofibroblast-Like, Hepatic Stellate Cells: A Critical Signaling Crossroad Sustaining Liver Fibrosis

Fibrogenic progression of chronic liver disease, whatever the etiology, is characterized by persistent chronic parenchymal injury, chronic activation of inflammatory response, and sustained activation of liver fibrogenesis, and of pathological wound healing response. A critical role in liver fibroge...

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Bibliographic Details
Main Authors: Beatrice Foglia, Stefania Cannito, Claudia Bocca, Maurizio Parola, Erica Novo
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:International Journal of Molecular Sciences
Subjects:
ERK pathway
hepatic stellate cells
liver myofibroblasts
liver fibrosis
chronic liver diseases
antifibrotic strategies
Online Access:https://www.mdpi.com/1422-0067/20/11/2700

Internet

https://www.mdpi.com/1422-0067/20/11/2700

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