Peptide IPPKKNQDKTE ameliorates insulin resistance in HepG2 cells via blocking ROS-mediated MAPK signaling

Reactive oxygen species (ROS) has been found to play an important role in insulin resistance. Whether the improvement effects of the peptide IPPKKNQDKTE on hepatic insulin resistance were mediated by ROS elimination was examined in this study. Results showed that the high glucose-induced MAPK signal...

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Bibliographic Details
Main Authors: Jia-jia Song, Qian Wang, Min Du, Bin Chen, Xue-ying Mao
Format: Article
Language:English
Published: Elsevier 2017-04-01
Series:Journal of Functional Foods
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464617300774