SLC7A11 regulated by NRF2 modulates esophageal squamous cell carcinoma radiosensitivity by inhibiting ferroptosis

SLC7A11 regulated by NRF2 modulates esophageal squamous cell carcinoma radiosensitivity by inhibiting ferroptosis

Abstract Background Solute carrier family 7 member 11(SLC7A11) is a component of cysteine/glutamate transporter, which plays a key role in tumor growth; however, its underlying effect on radiosensitivity in esophageal squamous cell carcinoma (ESCC) remains unclear. This study aimed to clarify SLC7A1...

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Bibliographic Details
Main Authors: Lei Feng, Kaikai Zhao, Liangchao Sun, Xiaoyang Yin, Junpeng Zhang, Conghe Liu, Baosheng Li
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Journal of Translational Medicine
Subjects:
Esophageal squamous cell carcinoma
NRF2
SLC7A11
Ferroptosis
Prognosis
Online Access:https://doi.org/10.1186/s12967-021-03042-7

Internet

https://doi.org/10.1186/s12967-021-03042-7

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