Structural basis for Rab1 de-AMPylation by the Legionella pneumophila effector SidD.

The covalent attachment of adenosine monophosphate (AMP) to proteins, a process called AMPylation (adenylylation), has recently emerged as a novel theme in microbial pathogenesis. Although several AMPylating enzymes have been characterized, the only known virulence protein with de-AMPylation activit...

Full description

Bibliographic Details
Main Authors: Yang Chen, Igor Tascón, M Ramona Neunuebel, Chiara Pallara, Jacqueline Brady, Lisa N Kinch, Juan Fernández-Recio, Adriana L Rojas, Matthias P Machner, Aitor Hierro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3656104?pdf=render