Diabetes mellitus aggravates hemorrhagic transformation after ischemic stroke via mitochondrial defects leading to endothelial apoptosis.
Diabetes is a crucial risk factor for stroke and is associated with increased frequency and poor prognosis. Although endothelial dysfunction is a known contributor of stroke, the underlying mechanisms have not been elucidated. The aim of this study was to elucidate the mechanism by which chronic hyp...
Main Authors: | Keisuke Mishiro, Takahiko Imai, Sou Sugitani, Akira Kitashoji, Yukiya Suzuki, Toshinori Takagi, Huayue Chen, Yasunori Oumi, Kazuhiro Tsuruma, Masamitsu Shimazawa, Hideaki Hara |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4136737?pdf=render |
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