Modification of Gene Expression, Proliferation, and Function of OP9 Stroma Cells by Bcr-Abl-Expressing Leukemia Cells.

by Emmanuelle Supper, Suhail Tahir, Takahiko Imai, Joe Inoue, Nagahiro Minato
Published 2015-01-01

A novel free radical scavenger, NSP-116, ameliorated the brain injury in both ischemic and hemorrhagic stroke models

by Takahiko Imai, Sena Iwata, Daisuke Miyo, Shinsuke Nakamura, Masamitsu Shimazawa, Hideaki Hara
Published 2019-11-01

Nrf2 activator ameliorates hemorrhagic transformation in focal cerebral ischemia under warfarin anticoagulation

by Takahiko Imai, Toshinori Takagi, Akira Kitashoji, Keita Yamauchi, Masamitsu Shimazawa, Hideaki Hara
Published 2016-05-01

Identification and characterization of the direct interaction between methotrexate (MTX) and high-mobility group box 1 (HMGB1) protein.

by Yuki Kuroiwa, Yoichi Takakusagi, Tomoe Kusayanagi, Kouji Kuramochi, Takahiko Imai, Tomoko Hirayama, Ichiaki Ito, Michiteru Yoshida, Kengo Sakaguchi, Fumio Sugawara
Published 2013-01-01

Us3 kinase encoded by herpes simplex virus 1 mediates downregulation of cell surface major histocompatibility complex class I and evasion of CD8+ T cells.

by Takahiko Imai, Naoto Koyanagi, Ryo Ogawa, Keiko Shindo, Tadahiro Suenaga, Ayuko Sato, Jun Arii, Akihisa Kato, Hiroshi Kiyono, Hisashi Arase, Yasushi Kawaguchi
Published 2013-01-01

Diabetes mellitus aggravates hemorrhagic transformation after ischemic stroke via mitochondrial defects leading to endothelial apoptosis.

by Keisuke Mishiro, Takahiko Imai, Sou Sugitani, Akira Kitashoji, Yukiya Suzuki, Toshinori Takagi, Huayue Chen, Yasunori Oumi, Kazuhiro Tsuruma, Masamitsu Shimazawa, Hideaki Hara
Published 2014-01-01

Antitumour Effects of Astaxanthin and Adonixanthin on Glioblastoma

by Shohei Tsuji, Shinsuke Nakamura, Takashi Maoka, Tetsuya Yamada, Takahiko Imai, Takuya Ohba, Tomohiro Yako, Masahiro Hayashi, Ken Endo, Masanao Saio, Hideaki Hara, Masamitsu Shimazawa
Published 2020-09-01

TRAF6 establishes innate immune responses by activating NF-kappaB and IRF7 upon sensing cytosolic viral RNA and DNA.

by Hiroyasu Konno, Takuya Yamamoto, Kohsuke Yamazaki, Jin Gohda, Taishin Akiyama, Kentaro Semba, Hideo Goto, Atsushi Kato, Toshiaki Yujiri, Takahiko Imai, Yasushi Kawaguchi, Bing Su, Osamu Takeuchi, Shizuo Akira, Yasuko Tsunetsugu-Yokota, Jun-ichiro Inoue
Published 2009-05-01