Multi‐modal meta‐analysis of cancer cell line omics profiles identifies ECHDC1 as a novel breast tumor suppressor

Multi‐modal meta‐analysis of cancer cell line omics profiles identifies ECHDC1 as a novel breast tumor suppressor

Abstract Molecular and functional profiling of cancer cell lines is subject to laboratory‐specific experimental practices and data analysis protocols. The current challenge therefore is how to make an integrated use of the omics profiles of cancer cell lines for reliable biological discoveries. Here...

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Bibliographic Details
Main Authors: Alok Jaiswal, Prson Gautam, Elina A Pietilä, Sanna Timonen, Nora Nordström, Yevhen Akimov, Nina Sipari, Ziaurrehman Tanoli, Thomas Fleischer, Kaisa Lehti, Krister Wennerberg, Tero Aittokallio
Format: Article
Language:English
Published: Wiley 2021-03-01
Series:Molecular Systems Biology
Subjects:
cancer driver
data integration
multi‐omics data
reproducibility
synthetic lethality
Online Access:https://doi.org/10.15252/msb.20209526

Internet

https://doi.org/10.15252/msb.20209526

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