Metabolic Modeling of Cystic Fibrosis Airway Communities Predicts Mechanisms of Pathogen Dominance

Metabolic Modeling of Cystic Fibrosis Airway Communities Predicts Mechanisms of Pathogen Dominance

Cystic fibrosis (CF) is a genetic disease in which chronic airway infections and lung inflammation result in respiratory failure. CF airway infections are usually caused by bacterial communities that are difficult to eradicate with available antibiotics. Using species abundance data for clinically s...

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Bibliographic Details
Main Authors: Michael A. Henson, Giulia Orazi, Poonam Phalak, George A. O’Toole
Format: Article
Language:English
Published: American Society for Microbiology 2019-04-01
Series:mSystems
Subjects:
community metabolism
cystic fibrosis
metabolic modeling
metabolite cross-feeding
Online Access:https://doi.org/10.1128/mSystems.00026-19

Internet

https://doi.org/10.1128/mSystems.00026-19

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