The role of adipose tissue and excess of fatty acids in the induction of insulin resistance in skeletal muscle

Skeletal muscle is the main tissue responsible for insulin-stimulated glucose uptake. Consumption of a high-fat diet rich in saturated fats (HFD) and obesity are associated with accumulation of intramuscular lipids that leads to several disorders, e.g. insulin resistance (IRes) and type 2 diabetes (...

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Bibliographic Details
Main Authors: Agnieszka Błachnio-Zabielska, Sławomir Grycel, Marta Chacińska, Piotr Zabielski
Format: Article
Language:English
Published: Index Copernicus International S.A. 2016-11-01
Series:Postępy Higieny i Medycyny Doświadczalnej
Subjects:
Online Access:http://phmd.pl/gicid/01.3001.0009.6893